POLB anticorps (AA 1-335)
Aperçu rapide pour POLB anticorps (AA 1-335) (ABIN3022385)
Antigène
Voir toutes POLB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-335
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Séquence
- MSKRKAPQET LNGGITDMLT ELANFEKNVS QAIHKYNAYR KAASVIAKYP HKIKSGAEAK KLPGVGTKIA EKIDEFLATG KLRKLEKIRQ DDTSSSINFL TRVSGIGPSA ARKFVDEGIK TLEDLRKNED KLNHHQRIGL KYFGDFEKRI PREEMLQMQD IVLNEVKKVD SEYIATVCGS FRRGAESSGD MDVLLTHPSF TSESTKQPKL LHQVVEQLQK VHFITDTLSK GETKFMGVCQ LPSKNDEKEY PHRRIDIRLI PKDQYYCGVL YFTGSDIFNK NMRAHALEKG FTINEYTIRP LGVTGVAGEP LPVDSEKDIF DYIQWKYREP KDRSE
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human DNA Polymerase beta (NP_002681.1).
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Isotype
- IgG
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Indications d'application
- WB,1:200 - 1:1000,IHC,1:50 - 1:200,IF,1:20 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." dans: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).
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- POLB (Polymerase (DNA Directed), beta (POLB))
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Autre désignation
- POLB
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Sujet
- The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.,POLB,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,POLB
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Poids moléculaire
- 38 kDa
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ID gène
- 5423
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UniProt
- P06746
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Pathways
- Réparation de l'ADN
Antigène
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