Connexin 43/GJA1 anticorps (AA 233-382)
Aperçu rapide pour Connexin 43/GJA1 anticorps (AA 233-382) (ABIN3023088)
Antigène
Voir toutes Connexin 43/GJA1 (GJA1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 233-382
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Séquence
- FKGVKDRVKG KSDPYHATSG ALSPAKDCGS QKYAYFNGCS SPTAPLSPMS PPGYKLVTGD RNNSSCRNYN KQASEQNWAN YSAEQNRMGQ AGSTISNSHA QPFDFPDDNQ NSKKLAAGHE LQPLAIVDQR PSSRASSRAS SRPRPDDLEI
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 233-382 of human GJA1 (NP_000156.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze / thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Gastric electrical stimulation improves enteric neuronal survival." dans: International journal of molecular medicine, Vol. 40, Issue 2, pp. 438-446, (2018) (PubMed).
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: "Gastric electrical stimulation improves enteric neuronal survival." dans: International journal of molecular medicine, Vol. 40, Issue 2, pp. 438-446, (2018) (PubMed).
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- Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
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Autre désignation
- GJA1
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Sujet
- This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.,GJA1,AVSD3,CMDR,CX43,EKVP,GJAL,HLHS1,HSS,ODDD,PPKCA,EKVP3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Gap Junctions,Cytoskeleton,Immunology & Inflammation,Cardiovascular,Heart,Cardiac arrhythmias,GJA1
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Poids moléculaire
- 43 kDa
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ID gène
- 2697
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UniProt
- P17302
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Pathways
- Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
Antigène
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