HLA-ABC anticorps

N° du produit ABIN3023755

Cet anticorps anti-HLA-ABC est un anticorps Souris Monoclonal détectant HLA-ABC dans FACS, IF et WB. Adapté pour Humain, Souris et Non-Human Primate.

Aperçu rapide pour HLA-ABC anticorps (ABIN3023755)

Antigène: HLA-ABC

Reactivité: Humain, Souris, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-ABC est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

Clone: 246-B8-E7

Détail du produit anti-HLA-ABC anticorps

Attributs du produit: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Purification: Protein G affinity chromatography

Immunogène: Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal dilution of the HLA-ABC antibody should be determined by the researcher.\. Western blot: 1-2 μg/mL, Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the HLA-ABC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur HLA-ABC

Antigène: HLA-ABC

Autre désignation: HLA-ABC (MHC I)

Sujet: Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints