HLA-ABC anticorps
Aperçu rapide pour HLA-ABC anticorps (ABIN3023755)
Antigène
Voir toutes HLA-ABC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- HLA-ABC Antibody (MHC I) (azide and preservative free)
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Attributs du produit
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
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Purification
- Protein G affinity chromatography
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Immunogène
- Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.
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Isotype
- IgG2a, kappa
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Indications d'application
- Optimal dilution of the HLA-ABC antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the HLA-ABC antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- HLA-ABC
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Autre désignation
- HLA-ABC
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Sujet
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
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UniProt
- P30443
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Antigène
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