CD4 anticorps
Aperçu rapide pour CD4 anticorps (ABIN3024369)
Antigène
Voir toutes CD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Protein G affinity chromatography
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Immunogène
- Recombinant human CD4 protein was used as immunogen for the CD4 antibody.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal dilution of the CD4 antibody for a specific application should be determined by researcher.\. Flow Cytometry: 0.5-1 μg/10e6 cells,Immunofluorescence: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- CD4 antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD4
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Autre désignation
- CD4
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Sujet
- CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
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Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Antigène
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