PDE1C anticorps (C-Term)

N° du produit ABIN302536

Détail du produit anti-PDE1C anticorps

Antigène: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE1C est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects Phosphodiesterase 1C (PDE1C) at C-terminal domain. Mouse and Rat.

Purification: Immunoaffinity chromatography

Immunogène: PDE1C antibody was raised against synthetic peptide from C-terminal domain of human PDE1C.

Information d'application

Indications d'application: Immunohistochemistry on paraffin sections (5 μg/mL). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.21 mg/mL

Buffer: PBS containing 0.09 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur PDE1C

Antigène: PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))

Autre désignation: PDE1C (PDE1C Produits)

Synonymes: anticorps CG14940, anticorps CG14942, anticorps CG14943, anticorps CG14944, anticorps CG31757, anticorps CG31758, anticorps CG42325, anticorps CG44007, anticorps Dmel\\CG44007, anticorps Dmel_CG14940, anticorps Dmel_CG14943, anticorps Dmel_CG14944, anticorps Dmel_CG31757, anticorps Dmel_CG31758, anticorps Dmel_CG42325, anticorps PDE1C, anticorps PDE1c, anticorps GB13690, anticorps Hcam3, anticorps Phosphodiesterase 1c, anticorps phosphodiesterase 1C, anticorps calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, anticorps calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, anticorps phosphodiesterase 1C, calmodulin-dependent b, anticorps Pde1c, anticorps PDE1C, anticorps LOC724389, anticorps LOC100019026, anticorps pde1cb

Sujet: Phosphodiesterase 1C is a cAMP/cGMP dual-specific, calcium/calmodullin-dependent phosphodiesterase. PDE1C has been shown to affect vascular smooth muscle proliferation and atherosclerosis, insulin secretion regulation, spermatozoa development, and erectile dysfunction. At least five PDE1C isoforms have been reported, the expression of which are regulated in a tissue/cell-specific manner.Synonyms: 5'-cyclic nucleotide phosphodiesterase 1C, Calcium/calmodulin-dependent 3', Cam-PDE 1C, HCAM3, Phosphodiesterase 1C, Phosphodiesterase-1C calmodulin-dependent, hCam-3

ID gène: 5137

NCBI Accession: NP_001177985

UniProt: Q14123

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma