PODXL anticorps (Extracellular, Intracellular, Transmembrane Domain)

N° du produit ABIN3025406

Cet anticorps Souris Monoclonal détecte spécifiquement PODXL dans WB, FACS, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour PODXL anticorps (Extracellular, Intracellular, Transmembrane Domain) (ABIN3025406)

Antigène: PODXL (Podocalyxin-Like (PODXL))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PODXL est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: 3D3

Détail du produit anti-PODXL anticorps

Épitope: Extracellular, Intracellular, Transmembrane Domain

Fonction: Podocalyxin Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A human recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain was used as the immunogen for the Podocalyxin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Podocalyxin antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Podocalyxin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur PODXL

Antigène: PODXL (Podocalyxin-Like (PODXL))

Autre désignation: Podocalyxin

Sujet: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Pathways: Tube Formation