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CD47 anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement CD47 dans FACS, IF, IHC (p) et Func. Il présente une réactivité envers Humain et Souris.
N° du produit ABIN3026435

Aperçu rapide pour CD47 anticorps (ABIN3026435)

Antigène

Voir toutes CD47 Anticorps
CD47

Reactivité

  • 154
  • 56
  • 26
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Souris

Hôte

  • 95
  • 77
  • 9
  • 3
  • 1
Souris

Clonalité

  • 111
  • 69
  • 4
Monoclonal

Conjugué

  • 80
  • 14
  • 11
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD47 est non-conjugé

Application

  • 114
  • 96
  • 61
  • 56
  • 43
  • 26
  • 26
  • 22
  • 21
  • 18
  • 14
  • 13
  • 12
  • 10
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)

Clone

IAP-964-B6H12-2
  • Attributs du produit

    This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

    Purification

    Protein G affinity chromatography

    Immunogène

    Recombinant human protein (IAP/964) and intact CD47 purified from placenta (B6H12.2) were used as the immunogen for the CD47 antibody cocktail.

    Isotype

    IgG
  • Indications d'application

    Optimal dilution of the CD47 antibody cocktail should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min.\. Functional Activity (Order SAF formulation),Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Agent conservateur

    Azide free

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store the CD47 antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène

    CD47

    Autre désignation

    CD47

    Sujet

    This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50  kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
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