This antibody specifically reacts with a protein of 20-30 kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1), or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease.
Purification
Protein G affinity chromatography
Immunogène
Native protein from brain was used as the immunogen for this UchL1 antibody.
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the UchL1 antibody to be titered up or down for optimal performance.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the UchL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
This antibody specifically reacts with a protein of 20-30 kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1), or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease.