Caspase 1 anticorps (Large Subunit, N-Term)

N° du produit ABIN3028535

L’anticorps anti-Caspase 1 Polyclonal Lapin est utilisé pour la détection de Caspase 1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Caspase 1 anticorps (Large Subunit, N-Term) (ABIN3028535)

Antigène: Caspase 1 (CASP1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Caspase 1 anticorps

Épitope: Large Subunit, N-Term

Fonction: Caspase-1 Antibody (p20 subunit)

Séquence: CSLEEAQRIW KQKSAEIY

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human CASP1 (CSLEEAQRIWKQKSAEIY) was used as the immunogen for this Caspase-1 antibody. The sequence is from the large subunit.

Isotype: IgG

Information d'application

Indications d'application: Titration of the Caspase-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized Caspase-1 antibody can be stored at 4oC. After reconstitution, aliquot and store at -20oC. Repeated freeze/thaw steps should be avoided.

Détails sur Caspase 1

Antigène: Caspase 1 (CASP1)

Autre désignation: Caspase-1

Sujet: Caspase-1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, interleukin 18, and interleukin 33 precursor proteins. The Caspase-1 gene consists of 10 exons spanning at least 10.6 kb and is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas.

UniProt: P29466

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome