Cyclin D1 anticorps (AA 219-238)

N° du produit ABIN3028596

Cet anticorps anti-Cyclin D1 est un anticorps Lapin Polyclonal détectant Cyclin D1 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Cyclin D1 anticorps (AA 219-238) (ABIN3028596)

Antigène: Cyclin D1 (CCND1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin D1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cyclin D1 anticorps

Épitope: AA 219-238

Purification: Antigen affinity

Immunogène: Amino acids 219-238 (SPNNFLSCYRTTHFLSRVIK) were used as the immunogen for this Cyclin D1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Cyclin D1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Cyclin D1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Cyclin D1

Antigène: Cyclin D1 (CCND1)

Autre désignation: Cyclin D1

Sujet: D-type cyclins are regarded as essential links between cell environment and the core cell cycle machinery. Cyclin D1, the product of the human gene CCND1, is also known as BCL1. Cyclin D1 expression is regulated by the retinoblastoma protein. Expression of Cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. The CCND1 gene can function as an oncogene.

UniProt: P25322

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, ER-Nucleus Signaling