XBP1 anticorps (C-Term)

N° du produit ABIN302900

L’anticorps Lapin Polyclonal anti-XBP1 a été validé pour WB, IF et IHC (p). Il convient pour détecter XBP1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour XBP1 anticorps (C-Term) (ABIN302900)

Antigène: XBP1 (X-Box Binding Protein 1 (XBP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XBP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-XBP1 anticorps

Épitope: C-Term

Specificité: This antibody reacts to a 17 amino acid peptide from near the carboxy terminus of XBP-1.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide corresponding to a 17 amino acid peptide from near the Carboxy terminus of XBP-1.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections: 5 μg/mL. Western Blot: 1-2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline, containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at-20 °C for longer.

Détails sur XBP1

Antigène: XBP1 (X-Box Binding Protein 1 (XBP1))

Autre désignation: XBP1 / TREB5

Sujet: This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. The protein contains two domains commonly found in transcription factors that confer DNA binding and dimerization capability. This gene product was also separately identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. There is also a recent finding that the same agents that cause an ER stress response, the unfolded protein response, also increase transcription of this gene. This increase in transcription requires an ER stress response consensus binding element in the promoter.Synonyms: Tax-responsive element-binding protein 5, X-box-binding protein 1, XBP-1, XBP2

ID gène: 7494

NCBI Accession: NP_001073007

UniProt: P17861

Pathways: ER-Nucleus Signaling, Unfolded Protein Response