TICAM2 anticorps (C-Term)

N° du produit ABIN3029187

Cet anticorps anti-TICAM2 Polyclonal Lapin (ABIN3029187) détecte spécifiquement TICAM2 dans WB, ICC, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TICAM2 anticorps (C-Term) (ABIN3029187)

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TICAM2 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TICAM2 anticorps

Épitope: C-Term

Fonction: TRAM Antibody / TRAM1

Séquence: KFINFQLRRW REHSAFQA

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Translocating chain-associating membrane protein 1 (KFINFQLRRWREHSAFQA) was used as the immunogen for this TRAM antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the TRAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TRAM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur TICAM2

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Autre désignation: TRAM

Sujet: By crosslinking and reconstitution of canine proteoliposomes, followed by microsequencing and PCR screening of canine kidney and HeLa cell cDNA libraries, Gorlich et al.(1992) isolated cDNAs encoding TRAM (translocating chain-associating membrane protein). The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 8. Sequence analysis predicted that human TRAM is a 374-amino acid, 8-pass transmembrane protein that shares 95 % amino acid identity with the canine protein. Functional analysis indicated that the protein influences glycosylation and is stimulatory or required for the translocation of secretory proteins.

UniProt: Q15629

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades