WISP1 anticorps (C-Term)

N° du produit ABIN3029640

Détail du produit anti-WISP1 anticorps

Antigène: WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WISP1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human WNT1-Inducible Signaling Pathway Protein 1 (ADLESYPDFSEIAN) was used as the immunogen for this WISP1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the WISP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the WISP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur WISP1

Antigène: WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))

Autre désignation: WISP1 (WISP1 Produits)

Synonymes: anticorps CCN4, anticorps WISP1c, anticorps WISP1i, anticorps WISP1tc, anticorps WISP-1, anticorps WISP1, anticorps si:ch211-38f10.2, anticorps AW146261, anticorps Elm1, anticorps zgc:172276, anticorps WNT1 inducible signaling pathway protein 1, anticorps WNT1 inducible signaling pathway protein 1a, anticorps WNT1-inducible-signaling pathway protein 1-like, anticorps WNT1 inducible signaling pathway protein 1b, anticorps WISP1, anticorps wisp1a, anticorps Wisp1, anticorps LOC100627044, anticorps wisp1b

Sujet: WNT1-Inducible Signaling Pathway Protein 1, also known as CCN4, is a matricellular protein that in humans is encoded by the WISP1 gene. It is induced by WNT1 and belongs to the CCN family, which includes connective tissue growth factor, cysteine-rich-61, and nephroblastoma overexpressed(Tanaka et al., 2001). By use of radiation hybrid mapping panels, Pennica et al.(1998) mapped the gene to chromosome 8q24.1-q24.3, roughly 4 Mb distal to MYC. Pennica et al.(1998) found that two distinct systems demonstrated that WISP1 induction was associated with expression of WNT1. WISP1 genomic DNA was amplified in colon cancer cell lines and in human colon tumors, and its RNA was overexpressed in 84 % of tumors examined compared with patient-matched normal mucosa.

UniProt: O95388

Pathways: Signalisation WNT, Growth Factor Binding