CXCR4 anticorps (AA 31-43)

N° du produit ABIN3030515

L’anticorps Lapin Polyclonal anti-CXCR4 a été validé pour WB. Il convient pour détecter CXCR4 dans des échantillons de Humain.

Aperçu rapide pour CXCR4 anticorps (AA 31-43) (ABIN3030515)

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CXCR4 anticorps

Épitope: AA 31-43

Purification: Antigen affinity

Immunogène: Amino acids 31-43 (EENANFNKIFLPT) were used as the immunogen for this CXCR4 antibody.

Isotype: IgG

Information d'application

Indications d'application: Titration of the CXCR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CXCR4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CXCR4

Antigène: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Autre désignation: CXCR4

Sujet: Chemokine,CXC Motif, Receptor 4, also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. By PCR analysis of human/hamster hybrid cell DNA, Herzog et al.(1993) showed that the NPY3R gene is located on human chromosome 2. Feng et al.(1996) showed that transient expression of the gene allowed nonhuman cells coexpressing recombinant CD4 to undergo Env-CD4-mediated cell fusion and productive HIV-1 infection. Peled et al.(1999) demonstrated that SDF1 and its receptor CXCR4 are critical for murine bone marrow engraftment by human SCID repopulating stem cells. Treatment of human cells with anti-CXCR antibodies prevented engraftment.

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events