CDK4 anticorps (C-Term)
Aperçu rapide pour CDK4 anticorps (C-Term) (ABIN3030611)
Antigène
Voir toutes CDK4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Purification
- Antigen affinity
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Immunogène
- An amino acid sequence from the C-terminus of mouse Cdk4 (RISAFRALQHSYLHKEESDAE) was used as the immunogen for this Cdk4 antibody.
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Isotype
- IgG
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Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the Cdk4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the Cdk4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CDK4 (Cyclin-Dependent Kinase 4 (CDK4))
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Autre désignation
- Cdk4
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Sujet
- Cyclin-dependent kinase-4(CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells.
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UniProt
- P30285
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Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases, Regulation of Cell Size
Antigène
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