Growth Hormone 1 anticorps (AA 27-216)
Aperçu rapide pour Growth Hormone 1 anticorps (AA 27-216) (ABIN3031117)
Antigène
Voir toutes Growth Hormone 1 (GH1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 27-216
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Fonction
- Growth Hormone Antibody
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Purification
- Antigen affinity
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Immunogène
- Rat partial recombinant protein (AA 27-216) was used as the immunogen for this Growth Hormone antibody.
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Isotype
- IgG
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Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the Growth Hormone antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Growth Hormone antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Growth Hormone 1 (GH1)
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Autre désignation
- Growth Hormone
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Sujet
- Growth Hormone (GH) is mapped to 17q22-q24. Human growth hormone has a molecular mass of 22,005 and contains 191 amino acid residues with 2 disulfide bridges. Rat GH shares 98 % amino acid sequence homology with mouse. It binds two receptor molecules and thereby induces signal transduction through receptor dimerization. At high concentrations, GH acts as an antagonist because of a large difference in affinities at the respective binding sites.
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UniProt
- P01244
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Pathways
- Signalisation NF-kappaB, Signalistation JAK/STAT, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
Antigène
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