Integrin beta 2 anticorps (AA 17-382)

N° du produit ABIN3031376

L’anticorps anti-Integrin beta 2 Polyclonal Lapin est utilisé pour la détection de Integrin beta 2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS, WB et IHC (p).

Aperçu rapide pour Integrin beta 2 anticorps (AA 17-382) (ABIN3031376)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 2 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Integrin beta 2 anticorps

Épitope: AA 17-382

Fonction: MAC-1 Antibody / CD11b / ITGAM

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 17-382) was used as the immunogen for this MAC-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the MAC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. This antibody has shown cross-reactivity with CD11c by ELISA.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MAC-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: MAC-1

Sujet: Macrophage-1 alpha (MAC-1) or CD11b are glycoproteins encoded by the ITGAM gene. It is mapped to 16p11.2. MAC-1 has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Additionally, it likely recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation