ITGA3 anticorps (N-Term)

N° du produit ABIN3031394

L’anticorps Lapin Polyclonal anti-ITGA3 a été validé pour WB et IHC (p). Il convient pour détecter ITGA3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ITGA3 anticorps (N-Term) (ABIN3031394)

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-ITGA3 anticorps

Épitope: N-Term

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human ITG3A (LFGYSVALHRQTERQQR) was used as the immunogen for this Integrin alpha 3 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Integrin alpha 3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur ITGA3

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Autre désignation: Integrin alpha 3

Sujet: ITGA3 (Integrin alpha 3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. It is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. It is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of the human protein increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, two potential cleavage sites, and the the N-terminal repeating units characteristic of ITGAs.

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex