KIT Ligand anticorps (AA 26-44)

N° du produit ABIN3031560

Cet anticorps anti-KIT Ligand est un anticorps Lapin Polyclonal détectant KIT Ligand dans WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour KIT Ligand anticorps (AA 26-44) (ABIN3031560)

Antigène: KIT Ligand (KITLG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIT Ligand est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KIT Ligand anticorps

Épitope: AA 26-44

Purification: Antigen affinity

Immunogène: Amino acids 26-44 (DEGICRNRVTNNVKDVTKLV-human) were used as the immunogen for this SCF antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the SCF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the SCF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur KIT Ligand

Antigène: KIT Ligand (KITLG)

Autre désignation: SCF

Sujet: Stem Cell Factor (also called kit-ligand, KL1, and Steel factor) is a cytokine that binds to the c-Kit receptor (CD117). SCF can exist both as a transmembrane protein and a soluble protein. It is localized to the long arm of human chromosome 12, between 12q14.3 and 12qter. SCF plays a role in the regulation of HSCs in the stem cell niche in the bone marrow. It has been shown to increase the survival of HSCs in vitro and contributes to the self renewal and maintenance of HSCs in-vivo. HSCs at all stages of development express the same levels of the receptor for SCF (c-Kit). The stromal cells that surround HSCs are a component of the stem cell niche, and they release a number of ligands, including SCF.

UniProt: P21583

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway