LCAT anticorps (AA 300-313)

N° du produit ABIN3031596

Cet anticorps anti-LCAT est un anticorps Lapin Polyclonal détectant LCAT dans WB. Adapté pour Humain et Rat.

Aperçu rapide pour LCAT anticorps (AA 300-313) (ABIN3031596)

Antigène: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LCAT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LCAT anticorps

Épitope: AA 300-313

Purification: Antigen affinity

Immunogène: Amino acids 300-313 (RDFQRFFADLHFEE-human) were used as the immunogen for this LCAT antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the LCAT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the LCAT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur LCAT

Antigène: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Autre désignation: LCAT

Sujet: LCAT (Lecithin: Cholesterol Acyltransferase), is an enzyme that converts free cholesterol into cholesteryl ester. Azoulay et al.(1987) used a cDNA clone corresponding to LCAT to assign the locus to 16q22 through the analysis of DNA from somatic cell hybrids and in situ hybridization. LCAT plays an important role in lipoprotein metabolism, especially in the process termed reverse cholesterol transport The enzyme is synthesized in the liver and circulates in blood plasma as a complex with components of high density lipoprotein(HDL). Cholesterol from peripheral cells is transferred to HDL particles, esterified through the action of LCAT on HDL, and incorporated into the core of the lipoprotein. The cholesterol ester is thereby transported to the liver(Jonas, 2000).

UniProt: P04180

Pathways: Lipid Metabolism