Plakophilin 2 anticorps (C-Term)

N° du produit ABIN3032241

Détail du produit anti-Plakophilin 2 anticorps

Antigène: Plakophilin 2 (PKP2)

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Plakophilin 2 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human PKP2 (KKTDFVNSRTAKAYHSLKD) was used as the immunogen for this Plakophilin 2 antibody (100% mouse homology).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Plakophilin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Plakophilin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Plakophilin 2

Antigène: Plakophilin 2 (PKP2)

Autre désignation: Plakophilin 2 (PKP2 Produits)

Synonymes: anticorps ARVD9, anticorps 1200008D14Rik, anticorps 1200012P04Rik, anticorps AA516617, anticorps Pkp2l, anticorps plakophilin 2, anticorps PKP2, anticorps Pkp2

Sujet: Plakophilin-2 is a protein that in humans is encoded by the PKP2 gene. This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. PKP2 is a constituent of the desmosomal plaque in simple epithelia, some stratified epithelia, and some nonepithelial cells. It is also enriched in the karyoplasm of cells of various types, including those lacking desmosomes. PKP proteins participate in linking cadherins to intermediate filaments in the cytoskeleton and this gene product may regulate the signaling activity of beta-catenin. Plakophilin-2 has been shown to interact with Desmoplakin, Plakoglobin and Desmoglein 1.

UniProt: Q99959

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2