SLIT1 anticorps (AA 487-504)

N° du produit ABIN303378

Détail du produit anti-SLIT1 anticorps

Antigène: SLIT1 (Slit Homolog 1 (SLIT1))

Épitope: AA 487-504

Reactivité: Humain, Souris, Poulet, Grenouille

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLIT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody recognises Slit Homolog 1 (SLIT1).

Réactivité croisée (Details): Species reactivity (expected):Chicken, Frog.
Species reactivity (tested):Human and Mouse.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic Peptide corresponding to aa 487-504 of Mouse SLIT-1 protein.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections (5 μg/mL). Immunofluorescence. Western Blot (1/500-1/2000). ELISA (1/10000-1/50000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid cycles of freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

Détails sur SLIT1

Antigène: SLIT1 (Slit Homolog 1 (SLIT1))

Autre désignation: SLIT1 (SLIT1 Produits)

Synonymes: anticorps Slil1, anticorps mKIAA0813, anticorps MEGF4, anticorps SLIL1, anticorps SLIT-1, anticorps SLIT3, anticorps megf4, anticorps slil1, anticorps slit-1, anticorps SLIT1, anticorps slit3, anticorps slit homolog 1 (Drosophila), anticorps slit guidance ligand 1, anticorps slit guidance ligand 1 S homeolog, anticorps slit homolog 1 protein, anticorps slit homolog 1b (Drosophila), anticorps slit homolog 1a (Drosophila), anticorps Slit1, anticorps SLIT1, anticorps slit1.S, anticorps slit1, anticorps LOC100459557, anticorps slit1b, anticorps slit1a

Sujet: SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.Synonyms: KIAA0813, MEGF4, Multiple epidermal growth factor-like domains protein 4, SLIL1, SLIT-1, Slit homolog 1 protein

ID gène: 6585

NCBI Accession: NP_003052

UniProt: O75093

Pathways: Regulation of Cell Size