CD33 anticorps (Biotin)

N° du produit ABIN303561

Cet anticorps anti-CD33 est un anticorps Souris Monoclonal détectant CD33 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD33 anticorps (Biotin) (ABIN303561)

Antigène: CD33

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD33 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: HIM3-4

Détail du produit anti-CD33 anticorps (Biotin)

Specificité: The antibody HIM3-4 reacts with CD33, a 67 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells, it is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells. HLDA V, WS Code M MA112. HLDA VI, WS Code M MA47.

Purification: Affinity Chromatography

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur CD33

Antigène: CD33

Autre désignation: CD33 / SIGLEC3

Sujet: CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia.Synonyms: Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, gp67

ID gène: 945

UniProt: P20138