FURIN anticorps (AA 591-794)

N° du produit ABIN3042409

Détail du produit anti-FURIN anticorps

Antigène: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Épitope: AA 591-794

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FURIN est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Furin(FURIN) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Furin(FURIN) detection. Tested with WB in Human.
Gene Name: furin (paired basic amino acid cleaving enzyme)
Protein Name: Furin

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Furin recombinant protein (Position: T591-L794). Human Furin shares 88% amino acid (aa) sequence identity with both mouse and rat Furin.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Furin is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur FURIN

Antigène: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Autre désignation: FURIN (FURIN Produits)

Synonymes: anticorps FURIN, anticorps furin, anticorps si:dkey-281a24.5, anticorps FUR, anticorps LOC100220259, anticorps PACE, anticorps spc1, anticorps xfurin, anticorps MGC82710, anticorps PCSK3, anticorps SPC1, anticorps 9130404I01Rik, anticorps Fur, anticorps Pcsk3, anticorps Pace, anticorps furin, paired basic amino acid cleaving enzyme, anticorps furin (paired basic amino acid cleaving enzyme) a, anticorps furin (paired basic amino acid cleaving enzyme) b, anticorps furin, paired basic amino acid cleaving enzyme L homeolog, anticorps furin (paired basic amino acid cleaving enzyme), anticorps FURIN, anticorps furina, anticorps furinb, anticorps furin, anticorps furin.L, anticorps Furin

Sujet: Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The Furin gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance.

Synonyms: Dibasic processing enzyme antibody|Dibasic-processing enzyme antibody|FES upstream region antibody|FUR antibody|FURIN antibody|Furin membrane associated receptor protein antibody|FURIN_HUMAN antibody|PACE antibody|Paired basic amino acid residue cleaving enzyme antibody|Paired basic amino acid residue-cleaving enzyme antibody|PCSK3 antibody|Proprotein convertase subtilisin/kexin type 3 antibody|SPC1 antibody

ID gène: 5045

UniProt: P09958

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway