Kallikrein 4 anticorps (AA 31-254)

N° du produit ABIN3042476

L’anticorps Lapin Polyclonal anti-Kallikrein 4 a été validé pour WB. Il convient pour détecter Kallikrein 4 dans des échantillons de Humain.

Aperçu rapide pour Kallikrein 4 anticorps (AA 31-254) (ABIN3042476)

Antigène: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kallikrein 4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Kallikrein 4 anticorps

Épitope: AA 31-254

Fonction: Anti-Kallikrein 4/KLK4 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Kallikrein 4/KLK4 Antibody Picoband® (ABIN3042476). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Kallikrein 4 recombinant protein (Position: I31-S254).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
1. Klokk, T. I., Kilander, A., Xi, Z., Waehre, H., Risberg, B., Danielson, H. E., Saatcioglu, F. Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer. Cancer Res. 67: 5221-5230, 2007. 2. Nelson PS, Gan L, Ferguson C, Moss P, Gelinas R, Hood L, Wang K (March 1999). 3. Simmer JP, Fukae M, Tanabe T, Yamakoshi Y, Uchida T, Xue J, Margolis HC, Shimizu M, DeHart BC, Hu CC, Bartlett JD (June 2000).

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Kallikrein 4

Antigène: Kallikrein 4 (KLK4) (Kallikrein-Related Peptidase 4 (KLK4))

Autre désignation: KLK4

Sujet:

Synonyms: Kallikrein-4,3.4.21.-,Enamel matrix serine proteinase 1,Kallikrein-like protein 1,KLK-L1,Prostase,Serine protease 17,KLK4,EMSP1, PRSS17, PSTS,

Tissue Specificity: Expressed in prostate.

Background: Kallikrein-related peptidase 4, also known as PSTS or EMSP1, is a protein which in humans is encoded by the KLK4 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In particular, they may serve as biomarkers for both prostate cancer and breast cancer. It has been found that KLK4 is a proliferative factor with effects on gene expression and it may have a role in prostate cancer development and progression.

Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

Poids moléculaire: 27 kDa

ID gène: 9622

UniProt: Q9Y5K2

Pathways: Système du Complément