PIN1 anticorps (AA 1-163)
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- Antigène Voir toutes PIN1 Anticorps
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
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Épitope
- AA 1-163
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PIN1 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1(PIN1) detection. Tested with WB in Human,Mouse,Rat.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1(PIN1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Protein Name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 - Purification
- Immunogen affinity purified.
- Immunogène
- E.coli-derived human Pin1 recombinant protein (Position: M1-E163). Human Pin1 shares 95% amino acid (aa) sequence identity with mouse Pin1.
- Isotype
- IgG
- Top Product
- Discover our top product PIN1 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Pin1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
- Autre désignation
- PIN1 (PIN1 Produits)
- Synonymes
- anticorps DOD, anticorps UBL5, anticorps dod, anticorps ubl5, anticorps pin1, anticorps pin1a, anticorps 0610025L01Rik, anticorps D9Bwg1161e, anticorps pin1b, anticorps zgc:73206, anticorps PPIase pin1, anticorps MdPin1, anticorps Pin1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog, anticorps protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1, anticorps peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog, anticorps peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, anticorps peptidyl-prolyl cis-trans isomerase Pin1, anticorps PIN1, anticorps Pin1, anticorps pin1, anticorps pin1.S, anticorps pin1.L, anticorps ppiD, anticorps PITG_11123, anticorps LOC103419188
- Sujet
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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, also called DOD, is an enzyme that in humans is encoded by the PIN1 gene. It is mapped to 19p13.2. The enzyme binds to a subset of proteins and thus plays a role as a post phospho PIN1rol in regulating protein function. Studies have shown that the deregulation of PIN1 may play a pivotal role in various diseases. Notably, the up-regulation of PIN1 may be implicated in certain cancers, and the down-regulation of Pin1 may be implicated in Alzheimer's disease. Inhibitors of PIN1 may have therapeutic implications for cancer and immune disorders. PIN1 activity regulates the outcome of proline-directed kinase (e.g. MAPK, CDK or GSK3) signalling and consequently regulates cell proliferation (in part through control of cyclin D1 levels and stability) and cell survival. PIN1 also has an essential role in maintaining cell proliferation and regulating cyclin D1 function.
Synonyms: DOD antibody|DODO, Drosophila, homolog of antibody|FLJ40239 antibody|FLJ77628 antibody|MGC10717 antibody|NIMA interacting 1 antibody|Peptidyl prolyl cis trans isomerase NIMA interacting 1 antibody|Peptidyl prolyl cis/trans isomerase NIMA interacting antibody|Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody|Peptidyl-prolyl cis-trans isomerase pin1 antibody|Peptidylprolyl cis/trans isomerase NIMA interacting 1 antibody|Pin 1 antibody|Pin1 antibody|PIN1_HUMAN antibody|PPIase Pin1 antibody|Prolyl isomerase antibody|Protein (peptidylprolyl cis/trans isomerase) NIMA interacting 1 antibody|Protein NIMA interacting 1 antibody|Rotamase Pin1 antibody|UBL 5 antibody|UBL5 antibody - ID gène
- 5300
- UniProt
- Q13526
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