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TBK1 anticorps (C-Term)

TBK1 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3042649
  • Antigène Voir toutes TBK1 Anticorps
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    Épitope
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 577-590, C-Term
    Reactivité
    • 77
    • 53
    • 27
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Rat
    Hôte
    • 73
    • 18
    • 1
    Lapin
    Clonalité
    • 70
    • 22
    Polyclonal
    Conjugué
    • 46
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TBK1 est non-conjugé
    Application
    • 59
    • 42
    • 25
    • 10
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase TBK1(TBK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Séquence
    YNEEQIHKFD KQKL
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase TBK1(TBK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: TANK-binding kinase 1
    Protein Name: Serine/threonine-protein kinase TBK1
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human NAK(577-590aa YNEEQIHKFDKQKL), identical to the related rat and mouse sequences.
    Isotype
    IgG
    Top Product
    Discover our top product TBK1 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for TBK1 is approximately 3 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    Autre désignation
    TBK1 (TBK1 Produits)
    Synonymes
    anticorps nak, anticorps t2k, anticorps TBK1, anticorps wu:fk70c05, anticorps zgc:136548, anticorps NAK, anticorps T2K, anticorps 1200008B05Rik, anticorps AI462036, anticorps AW048562, anticorps TANK binding kinase 1 L homeolog, anticorps TANK binding kinase 1, anticorps TANK-binding kinase 1, anticorps tbk1.L, anticorps TBK1, anticorps tbk1, anticorps Tbk1
    Sujet
    Serine/threonine-protein kinase TBK1, also called TANK-binding kinase 1 or NF-kappa-B-activating kinase is an enzyme that in humans is encoded by the TBK1 gene. The gene was assigned to human chromosome 12q14.2. Serine/threonine kinase plays an essential role in regulating inflammatory responses to foreign agents. TBK1 and NF-kappa-B signaling are essential in KRAS mutant tumors, and established a general approach for the rational identification of codependent pathways in cancer.

    Synonyms: EC 2.7.11.1 antibody|FLJ11330 antibody|NAK antibody|NF kappa B activating kinase antibody|NF kB activating kinase antibody|NF-kappa-B-activating kinase antibody|Serine/threonine protein kinase TBK 1 antibody|Serine/threonine protein kinase TBK1 antibody|Serine/threonine-protein kinase TBK1 antibody|T2K antibody|TANK antibody|TANK binding kinase 1 antibody|TANK-binding kinase 1 antibody|TBK 1 antibody|Tbk1 antibody|TBK1_HUMAN antibody|TRAF 2 antibody|TRAF2 antibody
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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