CDK1 anticorps (C-Term)

N° du produit ABIN3042681

Cité dans 10 publications. Cet anticorps anti-CDK1 Polyclonal Lapin (ABIN3042681) détecte spécifiquement CDK1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CDK1 anticorps (C-Term) (ABIN3042681)

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDK1 anticorps

Épitope: C-Term

Fonction: Anti-Cyclin-dependent kinase 1 CDK1 Antibody

Séquence: KMALNHPYFN DLDNQIKKM

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the relative rat,mouse sequences by two amino acids.

Attributs du produit: Anti-Cyclin-dependent kinase 1 CDK1 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human CDK1, different from the relative rat and mouse sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CDK1 (ABIN3042681)

Zhang, Yao, Luan, Zhao, Jing, Zhang, Hou, Zou: "APC/CCDC20 and APC/C play pivotal roles in the process of embryonic development in Artemia sinica." dans: Scientific reports, Vol. 6, pp. 39047, (2018) (PubMed).

Lin, Zhu, Sun, Yang, Sun, Li, Cui, Zheng, Yu: "Prostate cancer cell proliferation is suppressed by microRNA-3160-5p via targeting of F-box and WD repeat domain containing 8." dans: Oncology letters, Vol. 15, Issue 6, pp. 9436-9442, (2018) (PubMed).

Zhao, Zhao, Wang, Li, Zhang: "Glycyrrhizic Acid Prevents Sepsis-Induced Acute Lung Injury and Mortality in Rats." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 64, Issue 2, pp. 125-37, (2016) (PubMed).

Ren, Huang, Xu, Yang, Yang, Hu: "Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells." dans: Anti-cancer drugs, Vol. 26, Issue 6, pp. 599-611, (2015) (PubMed).

Guo, Cui, Peng, Fang, Zuo, Deng, Wang, Wu, Chen, Deng: "Dietary NiCl₂ causes G₂/M cell cycle arrest in the broiler's kidney." dans: Oncotarget, Vol. 6, Issue 34, pp. 35964-77, (2015) (PubMed).

Zheng, Liu, Liu, Ma, Zhou, Chen, Chang, Wang, Yang, He: "Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH?SY5Y human neuroblastoma cells." dans: Molecular medicine reports, Vol. 10, Issue 1, pp. 89-94, (2014) (PubMed).

Zeng, Xiang, Xue, Li, Ma, Ren, Xu, Jiao, Wang, Hu: "The cell death and DNA damages caused by the Tet-On regulating HSV-tk/GCV suicide gene system in MCF-7 cells." dans: Biomedicine & pharmacotherapy = Biome?decine & pharmacothe?rapie, Vol. 68, Issue 7, pp. 887-92, (2014) (PubMed).

Yang, Yang, Sun, Yan, Meng, Ma: "Alantolactone inhibits growth of K562/adriamycin cells by downregulating Bcr/Abl and P-glycoprotein expression." dans: IUBMB life, Vol. 65, Issue 5, pp. 435-44, (2013) (PubMed).

Lin, Fu, Zhao, Lin, Zou, Liu, Zhu, Wang, Yu: "Fbxw8 is involved in the proliferation of human choriocarcinoma JEG-3 cells." dans: Molecular biology reports, Vol. 38, Issue 3, pp. 1741-7, (2011) (PubMed).

Ye, Chen, Chen, Xie, Yang, Lou, Yu: "XJW20, a novel oxoindole derivative, induces G2/M arrest and apoptosis selectively in K562 leukemia cell line." dans: Chemico-biological interactions, Vol. 183, Issue 1, pp. 133-41, (2009) (PubMed).

Détails sur CDK1

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Autre désignation: CDK1

Sujet:

Background: CDC2, Cell Division Cycle 2, is also known as CDK1 (Cyclin-dependent Kinase 1). CDC2 is a catalytic subunit of a protein kinase complex, called the M-phase promoting factor, that induces entry into mitosis and is universal among eukaryotes. In HeLa cells CDC2 is the most abundant phosphotyrosine-containing protein and its phosphotyrosine content is subject to cell cycle regulation. CDC2 gene is located on chromosome 10.

Gene Full Name: cyclin dependent kinase 1

Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Poids moléculaire: 34 kDa

ID gène: 983

UniProt: P06493

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA