CDK7 anticorps (AA 31-346)
Aperçu rapide pour CDK7 anticorps (AA 31-346) (ABIN3042742)
Antigène
Voir toutes CDK7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 31-346
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Fonction
- Anti-Cdk7 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human Cdk7 shares 94.9%,96.1% amino acid (aa) sequence identity with mouse,rat Cdk7,respectively.
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Attributs du produit
- Anti-Cdk7 Antibody. Tested in WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Cdk7 recombinant protein (Position: D31-F346). Human Cdk7 shares 94.9% and 96.1% amino acid (aa) sequence identity with mouse and rat Cdk7, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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Autre désignation
- CDK7
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Sujet
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Background: Cyclin-dependent kinase 7, also known as cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. The gene was assigned to human chromosome 5q13.2. Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.
Gene Full Name: cyclin dependent kinase 7
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
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Poids moléculaire
- 39 kDa
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ID gène
- 1022
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UniProt
- P50613
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Pathways
- Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
Antigène
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