Neurotrophin 3 anticorps (Middle Region)

N° du produit ABIN3043024

Cet anticorps Lapin Polyclonal détecte spécifiquement Neurotrophin 3 dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 1 publication.

Aperçu rapide pour Neurotrophin 3 anticorps (Middle Region) (ABIN3043024)

Antigène: Neurotrophin 3 (NTF3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurotrophin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Neurotrophin 3 anticorps

Épitope: AA 174-189, Middle Region

Fonction: Anti-Neurotrophin 3/NTF3 Antibody Picoband®

Séquence: TVLGEIKTGN SPVKQY

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Neurotrophin 3/NTF3 Antibody (ABIN3043024). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Neurotrophin 3, identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Jones, K. R., Reichardt, L. F. : Molecular cloning of a human gene that is a member of the nerve growth factor family. Proc. Nat. Acad. Sci. 87: 8060-8064, 1990. 2. Rosenthal A., Goeddel D.V., Nguyen T., Lewis M., Shih A., Laramee G.R., Nikolics K., Winslow J.W.,"Primary structure and biological activity of a novel human neurotrophic factor.",Neuron 4:767-773(1990).

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-Neurotrophin 3 (ABIN3043024)

Guo, Zeng, Li, Huang, Liu, Li, Ding, Wu, Cai: "Cotransplant of neural stem cells and NT-3 gene modified Schwann cells promote the recovery of transected spinal cord injury." dans: Spinal cord, Vol. 45, Issue 1, pp. 15-24, (2007) (PubMed).

Détails sur Neurotrophin 3

Antigène: Neurotrophin 3 (NTF3)

Autre désignation: NTF3

Sujet:

Synonyms: Neurotrophin-3,NT-3,HDNF,Nerve growth factor 2,NGF-2,Neurotrophic factor,NTF3,

Tissue Specificity: Brain and peripheral tissues.

Background: Neurotrophin-3 is a member of a family of neurotrophic factors, that is closely related to both nerve growth factor and brain derived neurotrophic factor. These proteins are involved in the maintenance of the adult nervous system and affect development of neurons in the embryo when it is expressed in human placenta. NT3 deficient mice generated by gene targeting display severe movement defects of the limbs.

Sequence Similarities: Belongs to the enolase family.

Poids moléculaire: 47 kDa

UniProt: P20783

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway