Sonic Hedgehog anticorps (N-Term)

N° du produit ABIN3043230

Cet anticorps anti-Sonic Hedgehog est un anticorps Lapin Polyclonal détectant Sonic Hedgehog dans WB et IHC. Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Sonic Hedgehog anticorps (N-Term) (ABIN3043230)

Antigène: Sonic Hedgehog (SHH)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sonic Hedgehog est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Sonic Hedgehog anticorps

Épitope: AA 203-218, N-Term

Fonction: Anti-Sonic Hedgehog/SHH Antibody Picoband®

Séquence: ATVHLEQGGT KLVKDL

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Sonic Hedgehog/SHH Antibody (ABIN3043230). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Sonic Hedgehog, identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Tsukurov, O., Boehmer, A., Flynn, J., Nicolai, J.-P., Hamel, B. C. J., Traill, S., Zaleske, D., Mankin, H. J., Yeon, H., Ho, C., Tabin, C., Seidman, J. G., Seidman, C. : A complex bilateral polysyndactyly disease locus maps to chromosome 7q36. Nature Genet. 6: 282-286, 1994.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Sonic Hedgehog (ABIN3043230)

Dai, Ai, Du, Chen: "Sonic hedgehog expression correlates with distant metastasis in pancreatic adenocarcinoma." dans: Pancreas, Vol. 40, Issue 2, pp. 233-6, (2011) (PubMed).

Détails sur Sonic Hedgehog

Antigène: Sonic Hedgehog (SHH)

Autre désignation: SHH

Sujet:

Synonyms: Sonic hedgehog protein,SHH,HHG-1,Sonic hedgehog protein N-product,Sonic hedgehog protein C-product,SHH,

Tissue Specificity: Expressed in fetal intestine, liver, lung, and kidney. Not expressed in adult tissues.

Background: The mouse, chicken, and zebrafish Shh homologs are highly conserved. SHH expression was not detected in adult tissues examined. However, it was expressed in fetal intestine, liver, lung, and kidney. SHH gene is mapped to 7q. SHH mutations are not a frequent cause of isolated oral clefts.

Sequence Similarities: Belongs to the hedgehog family.

Poids moléculaire: 62-65 kDa

UniProt: Q15465

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development