RAC1 anticorps (C-Term)

N° du produit ABIN3043366

Détail du produit anti-RAC1 anticorps

Antigène: RAC1

Épitope: AA 169-189, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAC1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Ras-related C3 botulinum toxin substrate 1(RAC1) detection. Tested with WB in Human,Mouse,Rat.

Séquence: FDEAIRAVLC PPPVKKRKRK C

Réactivité croisée (Details): Cross-reactivity with Rac2 has not been validated. No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Ras-related C3 botulinum toxin substrate 1(RAC1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Protein Name: Ras-related C3 botulinum toxin substrate 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Rac1 (169-189aa FDEAIRAVLCPPPVKKRKRKC), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Rac1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-RAC1 (ABIN3043366)

Han, Zhuang, Chen, Zhu, Cai, Lu et al.: "Novel derivative of Paeonol, Paeononlsilatie sodium, alleviates behavioral damage and hippocampal dendritic injury in Alzheimer's disease concurrent with cofilin1/phosphorylated-cofilin1 and ..." dans: PLoS ONE, Vol. 12, Issue 9, pp. e0185102, (2017) (PubMed).

Shen, Yang, Yao, Sun, Chen, Mo, Shi, Chen, Liu: "Gadolinium promoted proliferation in mouse embryo fibroblast NIH3T3 cells through Rac and PI3K/Akt signaling pathways." dans: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 27, Issue 4, pp. 753-62, (2015) (PubMed).

Détails sur RAC1

Antigène: RAC1

Abstract: RAC1 Produits

Synonymes: anticorps Rac-1, anticorps TC-25, anticorps p21-Rac1, anticorps AL023026, anticorps D5Ertd559e, anticorps RAC2, anticorps CRAC1A, anticorps rac1, anticorps wu:fd16e02, anticorps zgc:55823, anticorps zgc:55917, anticorps zgc:86934, anticorps 2248, anticorps CG2248, anticorps D-Rac, anticorps D-Rac 1, anticorps D-Rac1, anticorps DRac, anticorps DRac1, anticorps DRacA, anticorps Dm Rac1, anticorps DmRAC, anticorps DmRAC1, anticorps Dmel\CG2248, anticorps Dmrac1, anticorps Drac, anticorps Drac1, anticorps Drac1a, anticorps DracA, anticorps GTPase Rac1, anticorps P40792, anticorps RAC1, anticorps Rac, anticorps Rac GTPase, anticorps Rac3, anticorps RacA, anticorps dRac, anticorps dRac1, anticorps drac1, anticorps rac, anticorps Xrac, anticorps mig5, anticorps p21-rac1, anticorps tc-25, anticorps Rac family small GTPase 1, anticorps RAS-related C3 botulinum substrate 1, anticorps ras-related C3 botulinum toxin substrate 1, anticorps ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1), anticorps Rac family small GTPase 1a, anticorps CG2248 gene product from transcript CG2248-RB, anticorps Rac family small GTPase 1 L homeolog, anticorps ras homolog family member G, anticorps RAC1, anticorps Rac1, anticorps rac1a, anticorps rac1.L, anticorps RHOG

Sujet: Rac1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells. It is encoded by the RAC1gene. This gene can produce a variety of alternatively splicedversions of the Rac1 protein, which appear to carry out different functions. This gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: Cell migration inducing gene 5 protein antibody|Cell migration-inducing gene 5 protein antibody|MGC111543 antibody|MIG5 antibody|Migration inducing gene 5 antibody|Migration inducing protein 5 antibody|p21 Rac1 antibody|p21-Rac1 antibody|Rac 1 antibody|RAC1 antibody|RAC1_HUMAN antibody|Ras like protein TC25 antibody|Ras related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody|Ras-like protein TC25 antibody|Ras-related C3 botulinum toxin substrate 1 antibody|Rho family small GTP binding protein Rac1 antibody|TC 25 antibody|TC25 antibody

ID gène: 5879

UniProt: P63000

Pathways: Signalisation WNT, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling