CD63 anticorps (AA 97-238)

N° du produit ABIN3043395

Détail du produit anti-CD63 anticorps

Antigène: CD63

Épitope: AA 97-238

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD63 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for CD63 antigen(CD63) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for CD63 antigen(CD63) detection. Tested with WB, IHC-P in Human.
Gene Name: CD63 Molecule
Protein Name: CD63 antigen

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD63 recombinant protein (Position: E97-M238). Human CD63 shares 74% and 73% amino acid (aa) sequence identity with mouse and rat CD63, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CD63 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-CD63 (ABIN3043395)

Ren, Wang, Yuan, Wang: "Dendritic cells loaded with HeLa-derived exosomes simulate an antitumor immune response." dans: Oncology letters, Vol. 15, Issue 5, pp. 6636-6640, (2018) (PubMed).

Du, Dong, Zhao, Fu, Wang, Chen, Ou, Li, Sun, Tang, Song: "Immunostimulatory and anti-neoplasm effects of a novel palindrome CpG oligodeoxynucleotide in mice." dans: Acta pharmacologica Sinica, Vol. 33, Issue 8, pp. 1047-54, (2012) (PubMed).

Détails sur CD63

Antigène: CD63

Autre désignation: CD63 (CD63 Produits)

Synonymes: anticorps C75951, anticorps ME491, anticorps Tspan30, anticorps LAMP-3, anticorps MLA1, anticorps OMA81H, anticorps TSPAN30, anticorps TSP29FA, anticorps CD63 antigen, anticorps CD63 molecule, anticorps Cd63 molecule, anticorps Cd63, anticorps CD63

Sujet: CD63 antigen is a protein that in humans is encoded by the CD63 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It is mapped to 12q13.2. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression.

Synonyms: Lysosomal associated membrane protein 3 antibody|CD 63 antibody|CD63 antibody|CD63 antigen (melanoma 1 antigen) antibody|CD63 antigen antibody|CD63 antigen melanoma 1 antigen antibody|CD63 Molecule antibody|CD63_HUMAN antibody|gp55 antibody|granulophysin antibody|LAMP 3 antibody|LAMP-3 antibody|LAMP3 antibody|LIMP antibody|Lysosomal-associated membrane protein 3 antibody|lysosome associated membrane glycoprotein 3 antibody|Mast cell antigen AD1 antibody|ME491 antibody|melanoma 1 antigen antibody|Melanoma associated antigen ME491 antibody|Melanoma associated antigen MLA1 antibody|Melanoma-associated antigen ME491 antibody|MGC72893 antibody|MLA 1 antibody|MLA1 antibody|NGA antibody|ocular melanoma associated antigen antibody|Ocular melanoma-associated antigen antibody|OMA81H antibody|PTLGP40 antibody|Tetraspanin 30 antibody|Tetraspanin-30 antibody|Tspan 30 antibody|Tspan-30 antibody|TSPAN30 antibody

ID gène: 967

UniProt: P08962