RAB10 anticorps (C-Term)

N° du produit ABIN3043448

L’anticorps Lapin Polyclonal anti-RAB10 a été validé pour WB. Il convient pour détecter RAB10 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RAB10 anticorps (C-Term) (ABIN3043448)

Antigène: RAB10 (RAB10, Member RAS Oncogene Family (RAB10))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RAB10 anticorps

Épitope: AA 153-185, C-Term

Fonction: Anti-RAB10 Antibody Picoband®

Séquence: AKANINIEKA FLTLAEDILR KTPVKEPNSE NVD

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-RAB10 Antibody Picoband® (ABIN3043448). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB10, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: RAB10 RAB10, member RAS oncogene family". 2. Chen YT, Holcomb C, Moore HP (Aug 1993). "Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag". Proc Natl Acad Sci U S A 90 (14): 6508-12. 3. He, H., Dai, F., Yu, L., She, X., Zhao, Y., Jiang, J., Chen, X., Zhao, S. Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues. Gene Expr. 10: 231-242, 2002.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur RAB10

Antigène: RAB10 (RAB10, Member RAS Oncogene Family (RAB10))

Autre désignation: RAB10

Sujet:

Synonyms: Ras-related protein Rab-10,RAB10,

Tissue Specificity: Expressed in breast, placenta, kidney, liver and pancreas. .

Background: Ras-related protein Rab-10 is a protein that in humans is encoded by the RAB10 gene. RAB10 belongs to the RAS superfamily of small GTPases. And RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking. The RAB10 gene is mapped to chromosome 2p23.1-p22.3 by radiation hybrid analysis. It was found that the purified recombinant GAP domain of human AS160 showed GAP activity with RAB2A, RAB8A, RAB10, and RAB14, but not with 14 other RABs. Immunoblot analysis showed that these RABs associated with Glut4-positive vesicles in mouse adipocytes. Thereby, it concluded that AK160 functions as a RAB GAP and that RABs may participate in GLUT4 translocation.

Poids moléculaire: 23 kDa

ID gène: 10890

UniProt: P61026

Pathways: Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome