ABI1 anticorps (N-Term)

N° du produit ABIN3043515

Cité dans 1 publication. Cet anticorps anti-ABI1 Polyclonal Lapin (ABIN3043515) détecte spécifiquement ABI1 dans WB, IHC, IF, FACS et ICC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ABI1 anticorps (N-Term) (ABIN3043515)

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-ABI1 anticorps

Épitope: N-Term

Fonction: Anti-SSH3BP1/ABI1 Antibody

Séquence: HGVKWLKAKH GNNQPARTGT LSRTN

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Attributs du produit: Anti-SSH3BP1/ABI1 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ABI1, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-ABI1 (ABIN3043515)

Cui, Yu, Dong, Chen, Zhang, Liu: "Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma." dans: Medical oncology (Northwood, London, England), Vol. 27, Issue 3, pp. 632-9, (2010) (PubMed).

Détails sur ABI1

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Autre désignation: ABI1

Sujet:

Background: SSH3BP1 is also known as ABI1. ABI1 is a human homolog of mouse Abl-interactor-1 (Abi1), mapped on 10p11.2. ABI1 participates in the transduction of signals from Ras to Rac by regulating Rac-specific guanine nucleotide exchange factor (GEF) activities. It dramatically promoted ABL1-mediated tyrosine phosphorylation of MENA, but not of other substrates. Abi-1 regulates c-Abl-mediated phosphorylation of Mena by interacting with both proteins. ABI1 plays a role in the leukemogenesis by translocating to MLL.

Gene Full Name: abl interactor 1

Sequence Similarities: Belongs to the ABI family.

Poids moléculaire: 65 kDa

ID gène: 10006

UniProt: Q8IZP0

Pathways: Signalisation RTK, Response to Water Deprivation, ER-Nucleus Signaling