DKK2 anticorps (AA 34-259)

N° du produit ABIN3043565

L’anticorps Lapin Polyclonal anti-DKK2 a été validé pour WB. Il convient pour détecter DKK2 dans des échantillons de Humain et Rat.

Aperçu rapide pour DKK2 anticorps (AA 34-259) (ABIN3043565)

Antigène: DKK2 (Dickkopf 2 Homolog (DKK2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DKK2 anticorps

Épitope: AA 34-259

Fonction: Anti-DKK2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-DKK2 Antibody Picoband® (ABIN3043565). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DKK2 recombinant protein (Position: K34-I259). Human DKK2 shares 96% amino acid (aa) sequence identity with mouse DKK2.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: DKK2 dickkopf homolog 2 (Xenopus laevis)". 2. Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA (Dec 1999). "Functional and structural diversity of the human Dickkopf gene family". Gene 238 (2): 301-13. 3. Wu W, Glinka A, Delius H, Niehrs C (2001). "Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling.". Curr. Biol. 10 (24): 1611-4.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur DKK2

Antigène: DKK2 (Dickkopf 2 Homolog (DKK2))

Autre désignation: DKK2

Sujet:

Synonyms: Dickkopf-related protein 2,Dickkopf-2,Dkk-2,hDkk-2,DKK2,UNQ682/PRO1316,

Tissue Specificity: Expressed in heart, brain, skeletal muscle and lung.

Background: Dickkopf-related protein 2 is a protein that in humans is encoded by the DKK2 gene. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).

Sequence Similarities: Belongs to the DAXX family.

Poids moléculaire: 28 kDa

ID gène: 27123

Pathways: Signalisation WNT