DKK2 anticorps (AA 34-259)
Aperçu rapide pour DKK2 anticorps (AA 34-259) (ABIN3043565)
Antigène
Voir toutes DKK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 34-259
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Fonction
- Anti-DKK2 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-DKK2 Antibody (ABIN3043565). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human DKK2 recombinant protein (Position: K34-I259). Human DKK2 shares 96% amino acid (aa) sequence identity with mouse DKK2.
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL, Human, Rat
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Autre désignation
- DKK2
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Sujet
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Synonyms: Dickkopf-related protein 2,Dickkopf-2,Dkk-2,hDkk-2,DKK2,UNQ682/PRO1316,
Tissue Specificity: Expressed in heart, brain, skeletal muscle and lung.
Background: Dickkopf-related protein 2 is a protein that in humans is encoded by the DKK2 gene. This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).
Sequence Similarities: Belongs to the DAXX family.
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Poids moléculaire
- 28 kDa
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ID gène
- 27123
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Pathways
- Signalisation WNT
Antigène
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