Angiopoietin 1 anticorps (AA 16-350)

N° du produit ABIN3043724

1 publication est disponible pour ce produit. L’anticorps anti-Angiopoietin 1 Polyclonal produit chez le Lapin a été validé pour WB. Il convient pour la détection de Angiopoietin 1 dans des échantillons provenant de Humain. }

Aperçu rapide pour Angiopoietin 1 anticorps (AA 16-350) (ABIN3043724)

Antigène: Angiopoietin 1 (ANGPT1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiopoietin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Angiopoietin 1 anticorps

Épitope: AA 16-350

Fonction: Anti-Angiopoietin 1/ANGPT1 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Angiopoietin 1/ANGPT1 Antibody (ABIN3043724). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Angiopoietin 1 recombinant protein (Position: H16-N350). Human Angiopoietin 1 shares 96% amino acid (aa) sequence with both mouse and rat Angiopoietin 1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-Angiopoietin 1 (ABIN3043724)

Sun, Wang, Cheng, Wang, Li, Xue, Wang, Ai, Zhang, Xu, Wang, Ji: "Morroniside improves microvascular functional integrity of the neurovascular unit after cerebral ischemia." dans: PLoS ONE, Vol. 9, Issue 6, pp. e101194, (2014) (PubMed).

Détails sur Angiopoietin 1

Antigène: Angiopoietin 1 (ANGPT1)

Autre désignation: ANGPT1

Sujet:

Synonyms: Angiopoietin-1,ANG-1,ANGPT1,KIAA0003,

Tissue Specificity: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis. .

Background: Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. Angiopoietin 1 is mapped to 8q23.1. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.

Sequence Similarities: Contains 1 fibrinogen C-terminal domain.

Poids moléculaire: 65 kDa

ID gène: 284

UniProt: Q15389

Pathways: Signalisation RTK, Glycosaminoglycan Metabolic Process