PTH1R anticorps (C-Term)

N° du produit ABIN3043983

Cité dans 3 publications. Cet anticorps anti-PTH1R Polyclonal Lapin (ABIN3043983) détecte spécifiquement PTH1R dans WB, IHC et ICC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PTH1R anticorps (C-Term) (ABIN3043983)

Antigène: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTH1R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Détail du produit anti-PTH1R anticorps

Épitope: AA 388-406, C-Term

Fonction: Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody

Séquence: KLRETNAGRC DTRQQYRKL

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Parathyroid Hormone Receptor 1/PTH1R Antibody (ABIN3043983). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Parathyroid Hormone Receptor 1, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PTH1R (ABIN3043983)

Ma, Wu, Jin: "The association between parathyroid hormone 1‑34 and the Wnt/β‑catenin signaling pathway in a rat model of osteoarthritis." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 8799-8807, (2018) (PubMed).

Wang, Wang, Dai, Chen, Yang, Dai, Ou, Wang, Lin: "Effects of Intermittent Administration of Parathyroid Hormone (1-34) on Bone Differentiation in Stromal Precursor Antigen-1 Positive Human Periodontal Ligament Stem Cells." dans: Stem cells international, Vol. 2016, pp. 4027542, (2016) (PubMed).

Li, He, Yao, Song, Zeng, Peng, Rosol, Deng: "TGF-? Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma." dans: Journal of Cancer, Vol. 6, Issue 6, pp. 511-8, (2015) (PubMed).

Détails sur PTH1R

Antigène: PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))

Autre désignation: PTH1R

Sujet:

Synonyms: Parathyroid hormone/parathyroid hormone-related peptide receptor,PTH/PTHrP type I receptor,PTH/PTHr receptor,Parathyroid hormone 1 receptor,PTH1 receptor,PTH1R,PTHR, PTHR1,

Tissue Specificity: Expressed in most tissues. Most abundant in kidney, bone and liver.

Background: Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTH1R, PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.

Sequence Similarities: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

Poids moléculaire: 66 kDa

UniProt: Q03431

Pathways: Regulation of Carbohydrate Metabolic Process