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ADRA2A anticorps (Middle Region)

ADRA2A Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3044006
  • Antigène Voir toutes ADRA2A Anticorps
    ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))
    Épitope
    • 15
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 213-228, Middle Region
    Reactivité
    • 38
    • 35
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 55
    • 1
    Lapin
    Clonalité
    • 56
    Polyclonal
    Conjugué
    • 21
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ADRA2A est non-conjugé
    Application
    • 32
    • 16
    • 13
    • 13
    • 12
    • 9
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Alpha-2A adrenergic receptor(ADRA2A) detection. Tested with WB in Human,Mouse,Rat.
    Séquence
    ILVYVRIYQI AKRRTR
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse, rat
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Alpha-2A adrenergic receptor(ADRA2A) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: adrenoceptor alpha 2A
    Protein Name: Alpha-2A adrenergic receptor
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence in the middle region of human alpha 2a Adrenergic Receptor(213-228aa ILVYVRIYQIAKRRTR), identical to the related mouse and rat sequences.
    Isotype
    IgG
    Top Product
    Discover our top product ADRA2A Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))
    Autre désignation
    ADRA2A (ADRA2A Produits)
    Synonymes
    anticorps ADRA2A, anticorps AW122659, anticorps Adra-2, anticorps Adra-2a, anticorps alpha(2A)AR, anticorps alpha2-C10, anticorps alpha2A, anticorps alpha2A-AR, anticorps ADRA2, anticorps ADRA2R, anticorps ADRAR, anticorps ALPHA2AAR, anticorps ZNF32, anticorps CA2-47, anticorps RATRG20, anticorps RG20, anticorps PORA2AR, anticorps adrenoceptor alpha 2A, anticorps alpha-2A adrenergic receptor-like, anticorps adrenergic receptor, alpha 2a, anticorps adra2a, anticorps ADRA2A, anticorps LOC100414445, anticorps Adra2a
    Sujet
    The alpha-2A adrenergic receptor, also known as ADRA2A denotes the human gene encoding it. This gene is mapped to 10q25.2. Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

    Synonyms: ADA2A_HUMAN antibody|ADRA2 antibody|ADRA2A antibody|ADRA2R antibody|ADRAR antibody|Adrenergic alpha 2A receptor antibody|Alpha 2 adrenergic receptor subtype C10 antibody|Alpha 2A adrenergic receptor antibody|Alpha 2AAR subtype C10 antibody|Alpha-2 adrenergic receptor subtype C10 antibody|alpha-2-adrenergic receptor, platelet type antibody|Alpha-2A adrenergic receptor antibody|Alpha-2A adrenoceptor antibody|Alpha-2A adrenoreceptor antibody|Alpha-2AAR antibody|ALPHA2AAR antibody|OTTHUMP00000058849 antibody|ZNF32 antibody
    UniProt
    P08913
    Pathways
    EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity
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