MCM5 anticorps (C-Term)

N° du produit ABIN3044244

Détail du produit anti-MCM5 anticorps

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Épitope: AA 720-734, C-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM5(MCM5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: EIQHRMQRKV LYRLK

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for DNA replication licensing factor MCM5(MCM5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: minichromosome maintenance complex component 5
Protein Name: DNA replication licensing factor MCM5

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human MCM5(720-734aa EIQHRMQRKVLYRLK), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur MCM5

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Autre désignation: MCM5 (MCM5 Produits)

Synonymes: anticorps 23.m06024, anticorps cdc46, anticorps xmcm5, anticorps CDC46, anticorps P1-CDC46, anticorps Afu5g02520, anticorps NCU01171.1, anticorps AA617332, anticorps AI324988, anticorps AL033333, anticorps Cdc46, anticorps Mcmd5, anticorps mCD46, anticorps mCDC46, anticorps mcm5, anticorps wu:fb34a06, anticorps CG4082, anticorps DmCDC46, anticorps DmCDC465, anticorps DmMCM5, anticorps DmMcm5, anticorps DmeMCM5, anticorps Dmel\\CG4082, anticorps MCM5, anticorps McM5, anticorps PCR4, anticorps DNA replication licensing factor MCM5, anticorps minichromosome maintenance complex component 5 S homeolog, anticorps minichromosome maintenance complex component 5, anticorps DNA replication licensing factor Mcm5, anticorps DNA replication licensing factor mcm5, anticorps MCM5 minichromosome maintenance deficient 5 (S. cerevisiae), anticorps minichromosome maintenance complex component 5 L homeolog, anticorps Minichromosome maintenance 5, anticorps DNA replication licensing factor mcm-5, anticorps BBOV_IV010040, anticorps mcm5.S, anticorps MCM5, anticorps AFUA_5G02520, anticorps NCU01171, anticorps PVX_084615, anticorps LOC5576119, anticorps CpipJ_CPIJ008678, anticorps Bm1_24480, anticorps CMU_022890, anticorps Mcm5, anticorps mcm5, anticorps TP01_0722, anticorps mcm5.L, anticorps mcm-5

Sujet: MCM5(MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 5),also known as CDC46, is a protein that in humans is encoded by the MCM5 gene. MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. And MCM5 is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The MCM5 gene is mapped on 22q12.3. The MCM5 gene contains 16 exons. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.

Synonyms: CDC 46 antibody|CDC46 antibody|CDC46 homolog antibody|Cell division cycle 46 antibody|DNA replication licensing factor antibody|DNA replication licensing factor MCM 5 antibody|DNA replication licensing factor MCM5 antibody|MCM 5 antibody|MCM5 antibody|MCM5_HUMAN antibody|MGC5315 antibody|Minichromosome maintenance complex component 5 antibody|Minichromosome maintenance deficient(S. cerevisiae) 5 antibody|Minichromosome maintenance deficient 5 antibody|Minichromosome maintenance deficient protein 5 antibody|P1 CDC46 antibody|P1-CDC46 antibody

UniProt: P33992

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA