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IGF1 anticorps (Middle Region)

IGF1 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3044390
  • Antigène Voir toutes IGF1 Anticorps
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    Épitope
    • 18
    • 15
    • 15
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-96, Middle Region
    Reactivité
    • 152
    • 68
    • 60
    • 22
    • 16
    • 9
    • 7
    • 3
    • 2
    • 1
    Humain, Rat
    Hôte
    • 130
    • 50
    • 10
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 139
    • 53
    Polyclonal
    Conjugué
    • 96
    • 29
    • 13
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IGF1 est non-conjugé
    Application
    • 145
    • 78
    • 66
    • 57
    • 42
    • 30
    • 27
    • 26
    • 26
    • 20
    • 15
    • 13
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Insulin-like growth factor I(IGF1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Séquence
    GSSSRRAPQT GIVDECC
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Insulin-like growth factor I(IGF1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: insulin-like growth factor 1(somatomedin C)
    Protein Name: Insulin-like growth factor I(IGF-I)
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence in the middle region of human IGF-1(80-96 aa GSSSRRAPQTGIVDECC), different from the mouse and rat sequences by one amino acid.
    Isotype
    IgG
    Top Product
    Discover our top product IGF1 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Wan, Wang, Xiong, Xiang, Li, Wang, Liu, Niu, Peng, Jiang, Chai: "Elucidating a molecular mechanism that the deterioration of porcine meat quality responds to increased cortisol based on transcriptome sequencing." dans: Scientific reports, Vol. 6, pp. 36589, (2018) (PubMed).

    Li, Zhang, Li, Zhao, Zhai, Yang, Kong, Wu, Chen, Teng: "miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cells." dans: Scientific reports, Vol. 7, pp. 45002, (2017) (PubMed).

    Huang, Zhou, Shi, Shao, Wang, Wang, Wang, Ding: "Effects of the IGF-1/PTEN/Akt/FoxO signaling pathway on male reproduction in rats subjected to water immersion and restraint stress." dans: Molecular medicine reports, Vol. 14, Issue 6, pp. 5116-5124, (2017) (PubMed).

    Tang, Liao, Xu, Zhang, Liu, Deng, Jiang, Fu, Chen, Zhou: "Estrogen and insulin-like growth factor 1 synergistically promote the development of lung adenocarcinoma in mice." dans: International journal of cancer. Journal international du cancer, Vol. 133, Issue 10, pp. 2473-82, (2013) (PubMed).

    Huang, Zhou, Wang, Wei, Zhang, Zhou, Hutz, Shi: "Effect of the IGF-1/PTEN/Akt/FoxO signaling pathway on the development and healing of water immersion and restraint stress-induced gastric ulcers in rats." dans: International journal of molecular medicine, Vol. 30, Issue 3, pp. 650-8, (2012) (PubMed).

    Chai, Guo, Wang, Fu, Guan, Tan, Ren, Yang: "Antibacterial effect of 317L stainless steel contained copper in prevention of implant-related infection in vitro and in vivo." dans: Journal of materials science. Materials in medicine, Vol. 22, Issue 11, pp. 2525-35, (2011) (PubMed).

  • Antigène
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    Autre désignation
    IGF1 (IGF1 Produits)
    Synonymes
    anticorps IGF-I, anticorps IGF1A, anticorps IGFI, anticorps C730016P09Rik, anticorps Igf-1, anticorps Igf-I, anticorps Npt2B, anticorps IGF-1, anticorps IGFIA, anticorps IGF-IB, anticorps igf1, anticorps IGF-1L, anticorps IGF-1a, anticorps IGF1, anticorps igf-1, anticorps igf1-A, anticorps igf1.S, anticorps xigf1, anticorps insulin like growth factor 1, anticorps insulin-like growth factor 1, anticorps insulin-like growth factor I, anticorps insulin like growth factor 1 L homeolog, anticorps IGF1, anticorps Igf1, anticorps LOC100136741, anticorps igf1, anticorps LOC678666, anticorps igf1.L, anticorps LOC104911603
    Sujet
    Insulin-like growth factor 1(IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al.(1990) placed the mouse IGF1 gene on chromosome 10.

    Synonyms: IBP1 antibody|IGF 1 antibody|IGF I antibody|IGF IA antibody|IGF IB antibody|IGF-I antibody|Igf1 antibody|IGF1_HUMAN antibody|IGFI antibody|IGFIA antibody|Insulin like growth factor 1(somatomedin C) antibody|Insulin like growth factor 1 antibody|Insulin like growth factor IA antibody|Insulin like growth factor IB antibody|Insulin-like growth factor I antibody|Mechano growth factor antibody|MGF antibody|OTTHUMP00000195080 antibody|OTTHUMP00000195081 antibody|OTTHUMP00000195082 antibody|OTTHUMP00000195083 antibody|OTTHUMP00000195084 antibody|Somatomedia C antibody|Somatomedin C antibody|Somatomedin-C antibody
    UniProt
    P05019
    Pathways
    Signalisation RTK, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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