NPM1 anticorps (N-Term)

N° du produit ABIN3044485

Détail du produit anti-NPM1 anticorps

Antigène: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Épitope: AA 22-41, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Fonction: Rabbit IgG polyclonal antibody for Nucleophosmin(NPM1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.

Séquence: ELKADKDYHF KVDNDENEHQ

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Nucleophosmin(NPM1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: nucleophosmin(nucleolar phosphoprotein B23, numatrin)
Protein Name: Nucleophosmin

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Nucleophosmin(22-41aa ELKADKDYHFKVDNDENEHQ), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NPM1

Antigène: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Autre désignation: NPM1 (NPM1 Produits)

Synonymes: anticorps B23, anticorps NPM, anticorps NO38, anticorps Npm, anticorps B23NP, anticorps npm4, anticorps npm, anticorps CG7917, anticorps CRP1, anticorps Crp1, anticorps Dmel\\CG7917, anticorps dNLP, anticorps dNLP-S, anticorps p22, anticorps npm1, anticorps sb:cb487, anticorps nucleophosmin 1, anticorps nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog, anticorps nucleophosmin 1b, anticorps Nucleophosmin, anticorps nucleophosmin, anticorps nucleophosmin (nucleolar phosphoprotein B23, numatrin), anticorps Nucleoplasmin, anticorps nucleophosmin 1a, anticorps NPM1, anticorps Npm1, anticorps npm1.L, anticorps npm1b, anticorps npm, anticorps Nlp, anticorps npm1a

Sujet: NPM1(Nucleophosmin/Nucleoplasmin family, member1), also known as NPM, nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. The NPM1 gene maps to chromosome 5q35. Chan et al.(1989) found that nucleophosmin is a nucleolar phosphoprotein that is more abundant in tumor cells than in normal resting cells. Stimulation of the growth of normal cells, e.g., mitogen activation of B lymphocytes, was accompanied by an increase in nucleophosmin protein level. They stated that nucleophosmin is likely involved in the assembly of ribosomal proteins into ribosomes. Electron microscopic study indicated that nucleophosmin is concentrated in the granular region of the nucleolus, where ribosome assembly occurs.

Synonyms: B23 antibody|MGC104254 antibody|NO38 antibody|NPM antibody|NPM_HUMAN antibody|NPM1 antibody|Nucleolar Phosphoprotein B23 antibody|Nucleolar protein NO38 antibody|Nucleophosmin(nucleolar phosphoprotein B23 numatrin) antibody|Nucleophosmin antibody|Nucleophosmin/nucleoplasmin family member 1 antibody|Numatrin antibody|OTTHUMP00000161024 antibody|OTTHUMP00000161025 antibody|OTTHUMP00000223397 antibody|OTTHUMP00000223398 antibody

UniProt: P06748

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly