PAK3 anticorps (N-Term)

N° du produit ABIN3044532

Cet anticorps anti-PAK3 Polyclonal Lapin (ABIN3044532) détecte spécifiquement PAK3 dans WB. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour PAK3 anticorps (N-Term) (ABIN3044532)

Antigène: PAK3

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PAK3 anticorps

Épitope: AA 13-49, N-Term

Fonction: Anti-PAK3 Antibody

Séquence: APPLRMNSNN RDSSALNHSS KPLPMAPEEK NKKARLR

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-PAK3 Antibody (ABIN3044532). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human PAK3, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Rat

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur PAK3

Antigène: PAK3

Autre désignation: PAK3

Sujet:

Synonyms: Serine/threonine-protein kinase PAK 3,2.7.11.1,Beta-PAK,Oligophrenin-3,p21-activated kinase 3,PAK-3,PAK3,OPHN3,

Tissue Specificity: Restricted to the nervous system. Highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. .

Background: Serine/threonine-protein kinase PAK 3?is an?enzyme?that in humans is encoded by the?PAK3?gene. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 62 kDa

ID gène: 5063

UniProt: O75914