JUP anticorps (AA 732-745)

N° du produit ABIN305904

Cet anticorps anti-JUP Polyclonal Chèvre (ABIN305904) détecte spécifiquement JUP dans WB, IHC, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris, Chien, Lapin, Singe et Hamster.

Aperçu rapide pour JUP anticorps (AA 732-745) (ABIN305904)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Souris, Chien, Lapin, Singe, Hamster

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-JUP anticorps

Épitope: AA 732-745

Specificité: Human JUP / Gamma Catenin. This antibody is expected to recognise both reported isoforms, as represented by NP_002221.1 and NP_068831.1.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Dog, Hamster, Panda, Rabbit (100%) Rat, Bat, Bovine, Pig, Opossum (93%) Elephant (86%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-GLRPPYPTADHMLA from the C-terminus of human JUP / Gamma Catenin (NP_002221.1, NP_068831.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Dog, Hamster, Panda, Rabbit (100%), Rat, Bat, Bovine, Pig, Opossum (93%), Elephant (86%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:32000), WB (0.2 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: JUP/CTNNG/Junction Plakoglobin

Sujet: Name/Gene ID: JUP
Family: Catenin

Synonyms: JUP, Desmoplakin-3, CTNNG, DPIII, Gamma catenin, Junction plakoglobin, PKGB, ARVD12, Catenin gamma, Desmoplakin III, DP3, PDGB

ID gène: 3728

NCBI Accession: NP_002221, NP_068831

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location