Retinoblastoma Protein (Rb) anticorps

N° du produit ABIN306636

Cet anticorps anti-Retinoblastoma Protein (Rb) Monoclonal Souris (Clone C36) (ABIN306636) détecte spécifiquement Retinoblastoma Protein (Rb) dans IP. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Poulet.

Aperçu rapide pour Retinoblastoma Protein (Rb) anticorps (ABIN306636)

Antigène: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé

Application: Immunoprecipitation (IP)

Clone: C36

Détail du produit anti-Retinoblastoma Protein (Rb) anticorps

Fonction: Mouse anti Human Rb (Retinoblastoma)

Attributs du produit: Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes.

Purification: Protein A/G Chromatography

Isotype: IgG1

Information d'application

Indications d'application: Applications: Immunoprecipitation

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur Retinoblastoma Protein (Rb)

Antigène: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Autre désignation: Rb (Retinoblastoma)

Sujet: Retinoblastoma-associated protein, pRb, pp110, p105-Rb

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases