Retinoblastoma Protein (Rb) anticorps

N° du produit ABIN306637

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoblastoma Protein (Rb) dans . Il présente une réactivité envers Humain, Souris, Rat, Poulet et Vison.

Aperçu rapide pour Retinoblastoma Protein (Rb) anticorps (ABIN306637)

Antigène: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reactivité: Humain, Souris, Rat, Poulet, Vison

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé

Application: Veuillez nous consulter SVP

Clone: XZ91

Détail du produit anti-Retinoblastoma Protein (Rb) anticorps

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Détails sur Retinoblastoma Protein (Rb)

Antigène: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Autre désignation: Rb (Retinoblastoma)

Sujet: The immunogen for the anti-human retinoblastoma (Rb) was a recombinant protein corresponding to amino acids 393 to 572 of the human retinoblastoma sequence. Retinoblastoma encodes a phosphorylated protein p110 and binds and regulates E2F transcription factors. Rb functions as a major cell cycle regulator by its ability to repress gene transcription by all three RNA polymerases. In its hypophosphorylated form, Rb binds to a subset of E2F containing complexes converting them to repressors preventing expression of E2F target genes. These complexes repress transcription via E2F binding elements in the promotersof cell cycle control genes, such as E2F-1, c-myc, and cdc2 genes. Synonyms: Retinoblastoma-associated protein, pRb, pp110, p105-Rb.

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases