VSX2 anticorps (C-Term)
Aperçu rapide pour VSX2 anticorps (C-Term) (ABIN306798)
Antigène
Voir toutes VSX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée
- Poulet, Humain, Souris, Rat
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Attributs du produit
- Ceh-10 homeodomain-containing homolog,Chx10 is a 46 kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus, and spinal cord.
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Purification
- Ammonium Sulfate Precipitation
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Isotype
- IgG
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Indications d'application
- Detects Chx10 by Western blot at 0.5 to 1 μg/mL. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Optimal concentration should be evaluated by serial dilutions. Suitable for use against recombinant proteins conjugated to OVA, GST, His tags and other.
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Restrictions
- For Research Use only
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Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide,Antibody raised against a recombinant protein corresponding to amino acids 264 to 361 derived from the C-terminal region of the human Chx10 protein conjugated to KLH.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- VSX2 (Visual System Homeobox 2 (VSX2))
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Autre désignation
- chx 10 (CT)
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UniProt
- P58304
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Pathways
- Dopaminergic Neurogenesis
Antigène
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