CD59 anticorps
Aperçu rapide pour CD59 anticorps (ABIN3071853)
Antigène
Voir toutes CD59 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
-
-
Fonction
- CD59 Unconjugated Antibody
-
Attributs du produit
- The clone BRA-10G binds with human CD59, a 20 kDa glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. CD59 regulates complement-mediated cell lysis and is a potent inhibitor of the complement membrane attack complex. CD59 is widely distributed on cells in all tissues. The CD59 expression on erythrocytes is important for their survival. Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH). This MAb is useful for study on GPI-anchored proteins, PNH and CD59 functions.
-
Purification
- Purified
-
Pureté
- >95 %
-
Immunogène
- Human K562 tumor cells
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
-
- CD59
-
Autre désignation
- CD59
-
NCBI Accession
- NP_000602, NP_001120695, NP_001120697, NP_001120698, NP_001120699, NP_976074, NP_976075, NP_976076
-
UniProt
- P13987
-
Pathways
- Système du Complément
Antigène
-