CD86 anticorps (PE)

N° du produit ABIN316891

Cet anticorps anti-CD86 est un anticorps Rat Monoclonal détectant CD86 dans FACS. Adapté pour Souris.

Aperçu rapide pour CD86 anticorps (PE) (ABIN316891)

Antigène: CD86

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD86 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: PO3

Détail du produit anti-CD86 anticorps (PE)

Specificité: This antibody recognises CD86 (B7-2). The PO3 clone has been reported to block some co-stimulatory functions of CD86.

Attributs du produit: Synonyms: CD28LG2, B70, FUN-1, BU63, T-lymphocyte activation antigen CD86, Activation B7-2antigen, CTLA-4 counter-receptor B7.2

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogène: Mouse B-cell line, BCL1.

Isotype: IgG2b

Information d'application

Indications d'application: Flow Cytometry: 1/10.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Reconstitute with 1.0 mL distilled water

Concentration: 0,1 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide, 1 % Bovine Serum Albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet: CD86 is an 80kD cell surface glycoprotein which is a member of the CD28/B7 family. In mouse, CD86 is expressed at high levels on peripheral blood monocytes, dendritic cells and at low levels on resting B and T-lymphocytes. Expression of CD86 on these cell populations can be increased upon activation. CD86 has been identified, along with CD80 (B7-1) as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA4). CD28 and CTLA4 are two receptors that have opposing functions in T-cell stimulation. Interaction of CD86 with CD28 promotes a number of T-cell activities, whereas the binding of CD86 to CTLA4 inhibits T-cell responses.Synonyms: Activation B7-2 antigen, B7.2, B70, BU63, CD28LG2, CTLA-4 counter-receptor B7.2, FUN-1, T-lymphocyte activation antigen CD86

ID gène: 12524

UniProt: P42082

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation